Doxycycline for Blepharokeratoconjunctivitis in Children
- Avoid in younger than age 8 due to concern about teeth yellowing and enamel hypoplasia
Dosing
- 40-200 mg/day have been used
- most evidence for 100 mg QD x 3 months or 50 mg QD x 8 months
- Duration: 4 weeks to 8 months
Side Effects
- Skin: photosensitivity and lesions
- GI: emesis, diarrhea, dyspepsia
- Stevens-Johnsons syndrome
- Supratheraputic INR in those taking coumadin
Contraindications
- pregnancy
- nursing mothers
- <8 years old
Oral Antibiotics for Meibomian Gland-Related Ocular Surface Disease
The end of a dogma: the safety of doxycycline use in young children for malaria treatment