superior_oblique_myokymia

Superior Oblique Myokymia

Uniocular paroxysms of small-amplitude, high-frequency rotary nystagmus.

  • Unknown.
  • May be regeneration of damage to trochlear nerve as it has been described in two patients who had superior oblique palsy. Arch Ophth Link
  • If there are other neurological symptoms there could be a tumor compressing the midbrain.

Patient History

  • Intermittent bursts of torsional and/or vertical diplopia or “shimmering” vision.
  • Episodes last several seconds to several minutes
  • Fatigue and stress may exacerbate

Exam

  • Rapid small-amplitude torsional eye movement, may only be seen at the slit lamp
  • Normal eye movements in absence of symptoms

None unless other neurologic signs then consider neuroimaging

None if the patient is not bothered

Medical Treatment

  • topical betaxolol (Betoptic 0.5%, Betoptic S 0.25%) BID- one report of success
  • carbamazepine (tegretol) 100 mg BID or TID to start and move to up to 200 mg TID as needed
    • potential side effects including leucopenia, acute renal failure, thromboembolism, and arrhythmias
    • blood counts (CBC, including platelets and reticulocytes), serum iron, liver function and renal function (urinalysis an BUN) needed to be monitored regularly
  • gabapentin 100mg QD or BID can titrate up to 300mg PO BID
  • propranolol 80 mg long acting
  • phenytoin (dilantin) 100mg PO TID
  • propranolol plus valproic acid
  • Medical treatment is often disappointing and fraught with side effects

Surgical Treatment

  • Tenectomy of Superior Oblique- a large portion needs to be removed
  • Combine above with prophylactic inferior oblique weakening
  • Some require a second surgery to treat residual diplopia with recession of contralateral inferior rectus with a nasal shift and possibly a nasal shift of both inferior rectus muscles if there is excyclotorsion
  • superior_oblique_myokymia.txt
  • Last modified: 2017/05/16 22:56
  • by oculoman