Show pageExport to PDFBack to top This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong. ====== Pediatric Anterior Uveitis ====== ==== Causes ==== * Primarily Ocular * Infectious * post-surgical (P. Acnes) * herpes viruses * Post-traumatic iritis * Fuchs heterochromic iridocyclitis * Lens-related * IOL related * Glaucomacyclitic crisis (Posner Schlossman) * Systemic Non-infectious Disease * [[jia_screening|Juvenile Idiopathic Arthritis]] * [[behcets|Behçet syndrome]] * [[tubulointerstitial_nephritis_uveitis|Tubulointerstitial Nephritis and Uveitis (TINU)]] * Sarcoidosis * Kawasaki syndrome * Juvenile onset spondyloarthropathies (HLA-B27 associated) * Juvenile Ankylosing spondilitis * Reactive arthritis * Inflammatory Bowel disease related * Psoriatic arthritis * Systemic Infectious Diseases * Post Infectious Autoimmune uveitis (streptococcal pharyngitis) * Herpes Viruses (VZV, HSV) * Syphilis * Tuberculosis * Lyme ==== Work-up for cases without an obvious cause ==== * Consider working up for: * Sarcoidosis * **angiotensin-converting enzyme (ACE)** and serum lysozyme levels * followed by chest x-ray * followed by Chest CT * Syphilis * Non-treponemal testing * **RPR** -or- * VDRL * Followed by treponemal testing * fluorescent treponemal antibody absorption (FTA-ABS) -or- * Treponema pallidum particle agglutination (TPPA) * Tuberculosis * **Serum QuantiFERON Gold** or PPD * Herpes viruses * **HSV PCR** * VZV PCR * JIA without significant arthritis- **ANA** * TINU * **urinary β2 microglobulin** * **BUN, Creatinine** * **urinalysis** (looking for proteinuria, normoglycemic glycosuria, microheaturia, sterile pyuria) * Lyme titers in endemic areas or travel to endemic areas * **Lyme DNA PCR** or Lyme Disease AB Western Blot * HLA-B27 in teenagers * Mascarade diseases (leukemia, lymphoma) * **CBC** ====Work up based on history and exam findings==== * Arthritis * ANA * Joint pain with chronic diarrhea and abdominal pain * HLA-B27 * Rash * Psoriasis * rash areas are red, pink, or purple, dry, itchy, and scaly * associated with arthritis * Lyme * erythema migrans * red, blue or pink circular or oval with clear center, expands over several days, may reach up to 12 inches and have a raised border * Travel to endemic areas, exposure to ticks * Borrelia burgdorferi antibodies IgG, IgM * Fever, Weight loss, fatigue, malaise, abdominal pain * urinary β2 microglobulin, BUN, Creatinine, UA. ANA, HLA-B27, CBC * Previous Strep throat (group A strep infection suspected * Antistreptolysin O titers ====Masquerades of Anterior Uveitis==== * Leukemia * [[retinoblastoma_international_classification|Retinoblastoma]] * Juvenile Xanthogranuloma ==== References ==== * [[https://www.aao.org/education/disease-review/pediatric-anterior-uveitis|AAO Pediatric Anterior Uveitis]] {{tag>ddx uveitis}} ddx uveitis