====== Classification of Uveitis ======  
(Standardization of Uveitis Nomenclature (SUN) working group scheme)

===== Anatomic Classification =====

^ Type          ^ Primary Site of Inflammation                       ^ Includes                                                                                                ^
| Anterior      | Anterior Chamber                                   | Iritis, Iridocyclitis, Anterior cyclitis                                                                |
| Intermediate  | Vitreous                                           | Pars Planitis, Posterior cyclitis, Hyalitis                                                             |
| Posterior     | Retina or Choroid                                  | Focal, multifocal or diffuse choriditis; Chorioretinitis; Retinochoroiditis, Retinitis, Neuroretinitis  |
| Panuveitis    | Anterior Chamber, Vitreous, and Retina or Choroid  |                                                                                                         |

===== Grading of Anterior Chamber Cells =====

^ Grade           ^ Cells in 1mm x 1 mm slit beam  ^
| 0               | <1                             |
| 0.5 + or Trace  | 1-5                            |
| 1+              | 6-15                           |
| 2+              | 16-25                          |
| 3+              | 26-50                          |
| 4+              | >50                            |

===== Grading of Anterior Chamber Flare =====
^ Grade  ^ Description                             ^
| 0      | None                                    |
| 1+     | Faint                                   |
| 2+     | Moderate (iris and lens details clear)  |
| 3+     | Marked (iris and lens details hazy)     |
| 4+     | Intense (fibrin or plastic aqueous)     |

===== Descriptors of Uveitis =====
^ Category ^ Descriptor ^ Comment ^
|Onset|Sudden| |
|:::|Insidious| |
|Duration|Limited|≤3 months duration|
|:::|Persistent|≥3 months duration|
|Course|Acute|Episode of sudden onset and limited duration|
|:::|Recurrent|Repeat episodes separated by periods of inactivity without therapy ≥3 months duration|
|:::|Chronic|Persistent with relapse <3 months after discontinuing therapy|

===== Grading Vitreous Cells =====
^ Grade          ^ Number of Vitreous cells  ^
| 0              | No cells                  |
| 0.5+ or trace  | 1-10                      |
| 1+             | 11-20                     |
| 2+             | 21-30                     |
| 3+             | 31-100                    |
| 4+             | >101                      |

===== Grading Vitreous Flare =====
^ Grade ^ Descriptors ^
|0|No inflammation present|
|0.5+|Trace inflammation present (slight blurring of optic nerve margins, normal striations and reflex of nerve fiber layer cannot be visualized)|
|1+|Mild blurring of the optic nerve and retinal vessels|
|2+|Optic nerve visible, borders blurred markedly|
|3+|Optic nerve head not visible|
|4+|  |


===== Activity of Uveitis =====
^ Term ^ Definition ^
|Inactive|Grade 0 cells (in anterior chamber)|
|Worsening activity|2-step increase in level of inflammation (i.e., anterior chamber cells, vitreous haze or increase from grade 3+ to 4+)|
|Improved activity|2-step decrease in level of inflammation (i.e., anterior chamber cells, vitreous haze or decrease to grade 0)|
|Remission|Inactive disease for ≥3 months after discontinuing all therapy for eye disease|

===== Reference =====

The Standardization of Uveitis Nomenclature (SUN) Working Group. [[http://www.ajo.com/article/S0002-9394(05)00407-1/fulltext|Am J Ophthalmol 2005;140:509-516]]

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