Mouth sores- aphthous ulcers usually first sign
Genital sores- (75%) small ulcers on scrotum or labia
Erythema Nodosum- painful red skin nodules
Also puss filled bumps in the skin
Arthritis
Ocular Inflammation (66%)
Rare associations
inflammation of the brain or spinal cord
blood clots, aneurism, GI vasculitis
Typically symptoms start in the 20's or 30's