Pediatric Intermediate Uveitis

• Most are idiopathic
• Juvenile Idiopathic Arthritis common
• Infections
  • Lyme disease (antibody test)
  • toxocariasis (antibody test)
  • syphilis (antibody test)
  • HTLV-1 (antibody test)
  • Bartonellosis (antibody test)
• Multiple sclerosis (MRI brain, HLA-DR2 and HLA-DR15)
• Sarcoidosis (ACE may be elevated normally, Chest Xray)
• Necrotizing systemic vasculitis
  • Behçets disease
  • Eales disease
• Collagen vascular diseases (HLA-B27)
  • Ankylosing Spondylitis
  • Inflammatory Bowel Diseases - (Ulcerative colitis, Crohn disease)
  • Psoriatic arthritis

• Endophthalmitis- suspect in the setting of recent surgery or intraocular injection, immunocompromised or parenteral nutrition or central line
• Intraocular lymphoma. (CBC with differential)

• Pars planitis

Reference: AAO Pediatric Intermediate Uveitis