PHACES Syndrome

• Posterior fossa abnormalities, and other brain abnormalities
• Hemangiomas- usually large on the face, can be anywhere in on the face or neck
• Arterial cerebrovascular anomalies
• Cardiac defects, aortic coarctation and other abnormalities
• Eye anomalies
• Sternal defects or supraumbilical raphe

• Retinal vascular abnormalities
• Persistent fetal retinal vessels
• “Morning-glory” disc.
• Peripapillary staphyloma.
• Optic nerve hypoplasia.

• Coloboma
• Congenital cataracts
• Sclerocornea
• Iris hypoplasia
• Iris vessel hypertrophy

• Microphthalmia
• Exophthalmos
• Congenital third nerve palsy
• Horner syndrome

Children's hospital of Wisconsin Article