Cocaine blocks reuptake of norepinepherine that is normally released from nerve endings. In a sympathetic lesion, norepinepherine is not released.
little or no effect
dilation
- Place not more than 2 drops of cocaine hydrochloride 10% in both eyes (2% for infants and children,4% and 5% can also work for adults)
- Measure anisocoria 50-60 minutes later
- 0.8 mm or greater anisocoria after the cocaine is highly suggestive of Horner syndrome
pupil held by membrane, scar or aberrant innervation Image
oculoman