Cocaine, Amphetamine and Apraclonidine Pupil effects in Horner Syndrome
Cocaine and Amphetamine
Apraclonidine
- Will cause “reversal” of anisocoria in Horner syndrome
- Dilation of the Horner pupil from apraclonidine binding to the Alpha-1 receptors that are up-regulated after 2-5 days