dacryoadenitis

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Dacryoadenitis

- inflammation of the lacrimal gland (main or accessory)

  • Infection
    • Viral most common
      • Epstein-Barr most common
      • Adenovirus
      • Varicella Zoster
      • Herpes Simplex
      • Rhinovirus
      • Cytomegalovirus
      • Mumps
    • Bacterial
      • Staph aureus
      • Streptococcus
      • Tuberculosis
    • Fungal
    • Parasitic
  • Autoimmune
    • Thyroid eye disease
    • IgG4 related disease
    • Granulomatosis with polyangiitis
    • Idiopathic orbital inflammation
    • Sarcoidosis
  • Neoplasms
    • Lymphoma
    • Adenoid cystic carcinoma
    • Pleomorphic adenoma
  • Symptoms
    • Pain in the superior lateral orbit with touch or eye movements
    • Droopy upper lid
    • Difficulty opening lid
    • Eye redness
    • Diplopia
    • Malaise
  • Signs
    • tenderness, edema, erythema, induction in superior lateral orbit
    • lid ptosis
    • conjunctival injection with or without chemosis
    • regional lymphadenopathy
    • proptosis
    • limitation of ocular motility
    • Vison loss rare
    • Fever
  • Imaging
    • CT orbits- for adults and older children
    • Chest radiograph (if considering sarcoidosis)
    • MRI orbits- for children and in recurrent disease in adults
  • Laboratory studies to consider
    • CBC with differential
    • ESR and/or C-reactive protein- evaluate inflammatory response
    • Conjunctival swab for viral PCR
    • ANA
    • SSA/SSb antibodies
    • Serum IgG4
    • Thyroid function test
    • Thyroid autoimmune antibodies
  • Biopsy
    • transeptal or trans-conjunctival biopsy of lacrimal gland in severe, persistent or recurrent cases
  • Surgery for abscess or mass
  • Antibiotic for bacterial infection
    • Broad spectrum
  • Oral Corticosteroids for idiopathic cases
  • Methotrexate or rituximab for refractory cases
  • Orbital radiation for refractory cases

Resources

  • dacryoadenitis.1720805916.txt.gz
  • Last modified: 2024/07/12 12:38
  • by oculoman