sjogren_syndrome

Sjögren Syndrome

Autoimmune disease of that affects the lacrimal and salivary glands causing dryness of the ocular surface and mucous membranes. It often seriously affects other organ systems, such as the lungs, kidneys, and nervous system.

  • Dry Mouth, fatigue, joint/muscle pain
  • Other autoimmune diseases: Rheumatoid Arthritis, Systemic Lupus Erythematosis, Scleroderma, Undifferentiated connective tissue disease, Reynaud, Hashimoto, Chron's Disease
  • Family History of autoimmune diseases
  • Schirmer test (unanesthetized) ≤ 5mm in 5 minutes
  • Ocular Surface Staining
    • Conjunctival lissamine green staining
ItemWeight/Score
Anti-SSA / Ro antibody positivity3
Focal lymphocytic sialadenitis with a focus score of ≥ 1 foci / 4 mm²3
Abnormal ocular staining score of ≥ 5 (or van Bijsterveld score of ≥ 4) 1
Shirmer's test (no local anesthetic) result of ≤ 5mm / 5 minutes1
Unstimulated salivary flow rate of ≤ 0.1 ml/minute1

Source:

  • sjogren_syndrome.txt
  • Last modified: 2023/03/07 15:44
  • by oculoman